Only a few neurons in the central nervous system use epinephrine. These are located together with noradre-nergic cells in the medulla oblongata, solitary tract nucleus, and medial longitudinal fascicle.

As we have seen, the synthesis of epinephrine is carried out in four enzymatic steps, the first two being common to dopamine, NE, and epinephrine, the first three being common to NE, and epinephrine, and the last needed only for the synthesis of epinephrine. Why are NE and epinephrine not made in dopaminergic neurons? The particular neurotrans-mitter produced is determined by the absence of the next enzyme. Thus, no products past dopamine are produced in dopaminergic neurons because dopa-mine b-hydroxylase is absent. Similarly, epinephrine is not produced in neurons that lack the methyl-transferase.

d. Serotonin (5-HT), an Indoleamine The essential amino acid L-tryptophan is oxidized to 5-hydroxy-tryptophan (5-HTP) by tryptophan hydroxylase, an enzyme homologous to tyrosine hydroxylase. The amino acid decarboxylase that operates in the cate-cholamine pathway also decarboxylates 5-HTP to serotonin.

Understanding And Treating Autism

Understanding And Treating Autism

Whenever a doctor informs the parents that their child is suffering with Autism, the first & foremost question that is thrown over him is - How did it happen? How did my child get this disease? Well, there is no definite answer to what are the exact causes of Autism.

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