Neurotransmitters

The known number of neurotransmitters occurring naturally in the human nervous system appears to grow progressively as our investigational tools become more sensitive and sophisticated. Currently, Table I represents a reasonable articulation of the known human neurotransmitters; the reader should be aware that, in another decade, this table will be, perhaps substantially, larger and will likely include a number of surprises as our knowledge base grows.

Literally, a book chapter could be written about each of the categories of neurotransmitters in Table I. However, the clinical focus of this article dictates that we restrict our discussion to those neurotransmitters that currently have utility in clinical medicine. Although intense research effort is being applied to evaluating the clinical significance of many, if not all, of the neurotransmitters in the table, our focus here will be on the amine category.

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