Ischemic Stroke A Background and Pathogenesis

Ischemia is defined as a reduction in blood flow. Progressive ischemia first disrupts neuronal functioning and later threatens cell viability. Although varia bility in normal CBF exists, levels below approximately 20 ml/100 g/min result in electrophysiological and functional deficits. CBF levels below 10 ml/100 g/min result in disruption of membrane integrity and cellular death (as seen within an area of completed infarction). Intermediate levels of CBF (between 10 and 20 ml/100 g/min) are seen within the ischemic penumbra, the area of potentially viable tissue immediately surrounding the infarction. Salvaging the potentially amenable ischemic penumbra remains an area of intense research.

Conquering Fear In The 21th Century

Conquering Fear In The 21th Century

The Ultimate Guide To Overcoming Fear And Getting Breakthroughs. Fear is without doubt among the strongest and most influential emotional responses we have, and it may act as both a protective and destructive force depending upon the situation.

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