Neuroreceptors The Other Side Of Neurotransmission

Receptors in the nervous system are essentially glyco-protein-based recognition sites for neurotransmitters. When interacting with a given receptor, a neurotransmitter can be a full or partial agonist, which stimulates maximal or submaximal effect, respectively, or an antagonist, which blocks the usual effect of stimulating the receptor. A neurotransmitter can also be an inverse agonist at a receptor, stimulating the receptor to have the opposite effect that it usually has when stimulated by an agonist (inverse agonists do not block receptors, they stimulate them). Chronic interaction between an agonist neurotransmitter and its receptor typically results in down-regulation (decreased production and distribution) of the receptors; chronic antagonism results in up-regulation (increased production and

Table II

Neurotransmitter Families

Table II

Neurotransmitter Families

Adrenergic receptors

a la, lb, lc, Id, 2a, 2b, 2c, 2d

Conquering Fear In The 21th Century

Conquering Fear In The 21th Century

The Ultimate Guide To Overcoming Fear And Getting Breakthroughs. Fear is without doubt among the strongest and most influential emotional responses we have, and it may act as both a protective and destructive force depending upon the situation.

Get My Free Ebook


Post a comment