Figure 9 Threshold of the Hodgkin-Huxley model can be explained by examining the stability of "fixed points.'' (a, b) Spiking behavior in the Hodgkin-Huxley model is very sensitive to V0, the initial value of voltage. Resting potential (—65 mV) is depicted by the dotted lines. (c) V (0.5), the time derivative of membrane potential at t = 0.5 msec, plotted vs V0. Also plotted are the contributions of GNa (dashed line), as well as GK and GL (dotted line), to V (0.5).The contribution of GL is minimal because this conductance is very small. (d) A magnified plot of V (0.5) vs V0. Two fixed points [points where V(0.5) = 0] are shown. As indicated by the arrows, the sign of V(0.5) makes the solution flow toward the open circle at (—65, 0), indicating stability; the solution flows away from the open triangle at (—59, 0), indicating instability. For V0> —59mV, an action potential will be generated.

Breaking Bulimia

Breaking Bulimia

We have all been there: turning to the refrigerator if feeling lonely or bored or indulging in seconds or thirds if strained. But if you suffer from bulimia, the from time to time urge to overeat is more like an obsession.

Get My Free Ebook

Post a comment