Astrocyte Cell Lineage

Mammalian species acquire their full complement of cortical neurons during the first half of gestation. Radial glia is established early in development at the time of neurogenesis, during the early gestational period, and accompanies neuroblasts during their migration to the cortex. In late gestational and early postnatal mammalian brain, the SVZ is the major source of astrocytes and oligodendrocytes, although astrocytes may also develop from radial glia. Remarkable recent data suggest that cells of the astrocyte lineage could have neural stem cell potential.

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