N Passing Urine

Passing urine (micturition) depends on activation of appropriate parasympathetic motoneurons in the sacral region of the spinal cord. Distention of the bladder activates afferent nerves whose spinal input tends to initiate micturition, but efficient emptying of the bladder requires descending activation which originates in brain stem preparasympathetic neurons located in the pontine micturition center, probably comprising a small group of neurons (Barrington's nucleus) located just medial to the locus coeruleus. Normally, micturition is delayed by descending inhibitory activity originating in the cerebral cortex.

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