Primary Cerebral Lymphoma

In the usual case, this tumor is derived from B lymphocytes and may be either uni- or multifocal. Brain lymphoma tends to occur in patients who are immunocompromised because of AIDS or the chronic use of immunosuppressive drugs. Periventricular white matter involvement is common, and lymphoma often appears in the differential diagnosis of AIDS patients with white matter lesions on MRI. Personality and cognitive changes along with focal motor deficits are common with this lesion. Because of the high radiosensitivity of this tumor, the prognosis is relatively favorable.

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