Progressive Multifocal Leukoencephalopathy

Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection of the cerebral white matter that frequently appears in patients with AIDS. The infectious agent is a member of the papavovirus family known as the JC virus. The virus infects oligodendro-cytes, and demyelination is seen pathologically. Multi-focal nonenhancing white matter involvement is typically seen on MRI scanning. The course of PML is invariably progressive, and attempts to treat the disease pharmacologically have been disappointing.

All About Alzheimers

All About Alzheimers

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