Single Photon Emission Computed Tomography

SPECT requires administration of a radionuclide that emits alpha particles. The alpha particles collide with surrounding electrons, which then emit photons that scatter into detectors. Computers then determine the location of the emitting sources and create tomo-graphic images mapping the quantity and location of emissions. The technique is useful for measuring CBF, both quantitatively and qualitatively. Quantitative measures of CBF may be obtained using the 133Xe inhalation technique, whereas relative measures of CBF are obtained following injection of [99mTc]d, 1-hexamethylpropylene amine oxime (HMPAO).

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