Spatial Distribution of Synapses

The various inputs to a neuron are distributed in a precise way on the postsynaptic cell. Virtually all neurons in the human CNS show the same location specificity: pyramidal cells, Purkinje cells, mitral cells, and motor neurons. The giant pyramidal cells in the hippocampus have perhaps the most striking lamination of afferents, as this input distribution is called. David Bodian, a pioneer in the study of synapses, had another term for it: mosaic segregation. The location of the end bulb or terminal bouton indicates the source of input, efficacy of action, and local biochemical diversity of the postsynaptic membrane.

Breaking Bulimia

Breaking Bulimia

We have all been there: turning to the refrigerator if feeling lonely or bored or indulging in seconds or thirds if strained. But if you suffer from bulimia, the from time to time urge to overeat is more like an obsession.

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