Conclusions

The catastrophic consequences that may result from cerebral edema have provided a perpetual impetus for research in the pathophysiology of this clinical entity. Elucidation of the underlying mechanisms allows for the classification of several forms of cerebral edema. The evolving knowledge of this combined entity emphasizes the critical role of water homeostasis in human physiology and its interaction with the complex biochemical alterations that underlie many neurologic diseases. Noninvasive neuroimaging techniques have revolutionized the identification of specific edema types, but these findings often do not correlate with clinical symptomatology. Therapy is usually reserved for secondary elevations in ICP, at a stage when the consequences prove life threatening and multiple edema types are present. Further diagnostic research efforts may provide early detection and detailed characterization of cerebral edema. This information allows the development of rational therapeutic interventions targeting biochemical factors that are specific to disease-state and temporal patterns. A combination of such interventions that modulate multiple aspects of cerebral edema may prove most efficacious.

Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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