Animal Models Of Neurodegeneration Are Necessary To Understand How Neurons

Animal models of neuronal degeneration are crucial for improving our understanding of the mechanisms and progressive stages of neuronal death. These models provide an experimental system to identify how nerve cells die in paradigms that mirror certain neuropatho-logical and clinical features of a neurological disorder that occurs in humans (Tables I and VIII). With animal models, the process of nerve cell death can be studied at the structural, biochemical, and molecular levels, and then subsequently the model can be used to test new therapies to prevent the degeneration of neurons in a biologically relevant system.

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