Prognostic Features

Much has been written about the natural history of MS. Because effective therapies will alter the natural history of the disease, this information is invaluable. Many patients expect to have a progressive disease when they are told a diagnosis of MS. In reality, 50% of patients will be walking without assistance 15 years after the diagnosis. As mentioned previously, the majority of patients present with relapsing-remitting disease. Approximately one-half of relapsing-remitting patients experience progression. Many features have been assessed as prognostic markers for future outcome, including the extent of disability at 5 years, age, sex, the extent of initial symptoms, complete or partial remission, type of symptoms at onset (e.g., optic neuritis, sensory symptoms, and cerebellar findings), and attack frequency in the first 2 and 5 years. Favorable prognostic factors are outlined in Table II. Because of the unpredictable nature of the disease, no firm predictions for an individual's course can be determined early in the disease. Of all predictors, the extent of disability at 5 years is most reliable, but patients who have a very mild early course may later develop significant disability. Death as a result of a relapse is extremely rare, although it may occur as a complication of the disease, such as pneumonia or suicide.

Understanding And Treating Autism

Understanding And Treating Autism

Whenever a doctor informs the parents that their child is suffering with Autism, the first & foremost question that is thrown over him is - How did it happen? How did my child get this disease? Well, there is no definite answer to what are the exact causes of Autism.

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