Prognostic Features

Much has been written about the natural history of MS. Because effective therapies will alter the natural history of the disease, this information is invaluable. Many patients expect to have a progressive disease when they are told a diagnosis of MS. In reality, 50% of patients will be walking without assistance 15 years after the diagnosis. As mentioned previously, the majority of patients present with relapsing-remitting disease. Approximately one-half of relapsing-remitting patients experience progression. Many features have been assessed as prognostic markers for future outcome, including the extent of disability at 5 years, age, sex, the extent of initial symptoms, complete or partial remission, type of symptoms at onset (e.g., optic neuritis, sensory symptoms, and cerebellar findings), and attack frequency in the first 2 and 5 years. Favorable prognostic factors are outlined in Table II. Because of the unpredictable nature of the disease, no firm predictions for an individual's course can be determined early in the disease. Of all predictors, the extent of disability at 5 years is most reliable, but patients who have a very mild early course may later develop significant disability. Death as a result of a relapse is extremely rare, although it may occur as a complication of the disease, such as pneumonia or suicide.

Adult Dyslexia

Adult Dyslexia

This is a comprehensive guide covering the basics of dyslexia to a wide range of diagnostic procedures and tips to help you manage with your symptoms. These tips and tricks have been used on people with dyslexia of every varying degree and with great success. People just like yourself that suffer with adult dyslexia now feel more comfortable and relaxed in social and work situations.

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