Antigen Clearance

Antony J Cutler and Kevin A Davies, Rheumatology Unit, Royal Postgraduate Medical School, Hammersmith Hospital, London

The clearance of exogenous antigens constitutes one of the primary functions of the immune system. Antigens are mainly eliminated by the cells of the fixed mononuclear phagocytic system. The mechanism of removal depends on the biological and physico-chemical properties of the antigen concerned, its mode of presentation to the immune system, and its ability to elicit a specific humoral or cellular immune response.

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