Antigens Cell Surface

Wolfgang J Rett ig, Dr Karl Thomae GmbH, Germany

The basic structure of the plasma membrane is a lipid bilayer with intercalated proteins and carbohydrate side-chains extending from the external membrane surface. Chemical studies with SDS-polyacrylamide gel electrophoresis, lectin chromatography and glycolipid analysis have shown that plasma mem branes isolated from various tissues differ widely in their protein and carbohydrate composition. However, by far the most detailed picture of plasma membrane diversity, especially with regard to the diversity displayed on the external membrane surface, has come from immunologic studies.

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