antibody recognition

Alternative exon usage

Figure 1 Human CD45. The variable exons 4, 5 and 6 are indicated. N represents site of potential AMinked glycosylation. C represents the location of cysteine residues in the extracellular domain.

the junction between exon 3 and 7; this is specific for the CD450 isoform. A similar reagent does not exist for mouse or rat CD45. Unlike CD45R0, however, the remaining CD45R antibodies are all capable of recognizing multiple isoforms (Table 1). This

Table 1 CD45 isoforms


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