Sporozoites injected during tick feeding are the infective stage; these then invade the host mononuclear leukocytes (see Figure 2). The target cells for T. parva sporozoites are mainly bovine T cells, while those for T. annulata are B lymphocytes and macrophages. The target cell types for other Theileria species have not been defined. Following entry, sporozoites differentiate into multinucleate schizonts. The
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