Clotting System

Arthur S Brecher, Department of Chemistry, Bowling Green State University, Bowling Green, Ohio, USA

The clotting system consists of a mixture of components including cells, fragments thereof, zymogens, their activation products and naturally occurring inhibitors, adhesive and structural proteins, phospholipids, lipids, cyclic and noncyclic nucleotides, hormones and inorganic cations, all of which are normally maintained in a state conducive to blood flow. Upon damage to the vascular wall with disruption of the monocellular layer of endothelial cells, exposing the subendothelial layer, and also permit ting bleeding, a series of events is initiated designed to produce clot formation. These homeostatic reactions lead to the generation of the primary platelet plug, followed by a clot principally containing cross-linked fibrin (secondary hemostasis). Subsequently, the blood vessel is repaired and the clot is dissolved by a mechanism which includes fibrinolysis.

100 Bowling Tips

100 Bowling Tips

Playing bowling with your friends can help you decide if it is indeed the hobby that you want to invest your time on today. Aside from that, it can help you get a better feel of the sport. More importantly, when you play with your friends, it would become a more fun activity, which you can look forward to each week.

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