Diagnostic relevance of tumor immunology

The use of panels of monoclonal antibodies (mAbs) for immunophenotyping tumor material is now well established and of great value in subtyping lymphomas and for determining the histiogenesis of undifferentiated tumors.

Antibodies directed against tumor-associated antigens have also been used for the immunolocalization of tumors by means of radiolabeled antibodies. So far, this conceptually appealing mode of imaging has failed to prove more effective than more conventional imaging techniques.

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