Disease associations

Immunoglobulin levels may also be associated with allotype and several studies have established that individuals homozygous for G2m(n) have higher IgG2 subclass levels than those homozygous for G2m(n"), heterozygotes having intermediate levels. Since protective immune responses to certain bacterial species are restricted to the IgG2 isotype, these

Table 3 Gm haplotypes characteristic for a Race
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