Doublestrand break repair

Figure 2 shows an example of a model for recom-binational repair of double-strand breaks in DNA. The two interacting molecules, or lengths of homology within molecules, are shown together in Figure 2A. Figure 2B shows the result of processing of the broken ends by polar single-strand exonucleases. The single-strand tails, in this diagram, are presumed to have 3' ends. Both tails may invade the homologous sequence forming two D loops (Figure 2C). The 3' ends may prime DNA synthesis, so that both nucleotide strands of the undamaged molecule are copied

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