Further reading

Conley ME, Larché M, Bonagura VR et al ( 1994) Hyper IgM syndrome associated with defective CD40-

mediated B cell activation. Journal of Clinical Investigation 94: 1404-1409.

Facchetti F, Appiani C, Salvi L, Levy J and Notarangelo LD (1995) [mmunohistologic analysis of ineffective CD40-CD40 ligand interaction in lymphoid tissue from patients with X-linked immunodeficiency with hyper-IgM. Abortive germinal center cell reaction and severe depletion of follicular dendritic cells. Journal of immunology 154: 6624-6633.

Fuleihan R, Ramesh N and Geha RS (1995) X-linked agammaglobulinemia and immunoglobulin deficiency with normal or elevated IgM: Immunodeficiencies of B cell development and differentiation. Advances in Immunology 60: 37-56.

Hollenbaugh D, Wu LH, Ochs HD et al (1994) The random inactivation of the X chromosome carrying the defective gene responsible for X-linked hyper IgM syndrome (X-HIM) in female carriers of HIGM. Journal of Clinical Investigation 94: 616-622.

Kawabe T, Naka T, Yoshida K et al (1994) The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. Immunity 1: 167-178.

Lin Q, Rohrer J, Allen RC et ai (1996) A single strand conformation polymorphism study of CD40 ligand. Efficient mutation analysis and carrier detection for X-linked hyper IgM syndrome. Journal of Clinical Investigation 97: 196-201.

Noel le RJ (1996) CD40 and its ligand in host defense. Immunity 4: 415-419.

Nonoyama S, Hollenbaugh D, Aruffo A, Ledbetter JA and

Ochs HD (1993) B cell activation via CD40 is required for specific antibody production by antigen-stimulated human B cells .Journal of Experimental Medicine 178: 1097-1102.

Notarangelo LD, Duse M and Ugazio AG ( 1992) Immunodeficiency with hyper-IgM (HIM). Immunodeficiency Review 3: 101-122.

Rieux-Laucat F, Le Diest F, Hivroz C et al (1995) Mutations in fas associated with human lympho-proliferative syndrome and autoimmunity. Science 268: 1347-1349.

Rosen FS, Kevy S, Merler F., Janewav CA and Gitlin 1) (1961) Recurrent bacterial infections and dysgamma-globulincmia: Deficiency of 7S gammaglobulins in the presence of elevated 19S gammaglobulins. Report of two cases. Pediatrics 28: 182-195.

Schattner EJ, Elkon KB, Yoo D-H et al (1995) CD40 ligation induces Apo-l/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-l/Fas pathway. Journal of Experimental Medicine 182: 1557-1565.

Thomas C, de Saint Basile G, Le Diest F et al (1995) Correction of X-linked hyper-IgM syndrome by allogeneic bone marrow transplantation. New England Journal of Medicine 333: 426-429.

Wiley JA and Harmsen AG (1995) CD40 ligand is required for resolution of Pneumocystis carinii pneumonia in mice. Journal of Immunology 155: 3525-3529.

Xu J, Foy TM, Laman JD et al (1994) Mice deficient for the CD40 ligand. Immunity 1: 42.3-43 1.

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