Further reading

Calnan BJ, Szychowski S, Chan FK, Cado D and Winoto A (1995) A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection. Immunity 3: 273-282. Chen C, Nagy Z, Radic MZ et al (1995) The site and stage of anti-DNA B-cell deletion. Nature 373: 252-255. Cyster JG and Goodnow CC (1995) Antigen-induced exclusion from follicles and anergy are separate and complementary process that influence peripheral B cell fate. Immunity 3: 691-701. Dhein J, Walczak H, Baumler C, Debatin KM and Krammer PH (1995) Autocrine T-cell suicide mediated by APO-l/(Fas/CD95). Nature 373: 438-441. Goodnow CC (1996) Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires. Proceedings of the National Academy of Sciences of the USA 93: 2264-2271.

Jacobson BA, Panka DJ, Nguyen KA, Erikson J, Abbas AK and Marshak-Rothstein A (1995). Anatomy of autoantibody production: dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice. Immunity 3: 509-519.

Murphy KM, Heimberger AB and Loh DY (1990) Induction by antigen of intrathymic apoptosis of CD4+CD8+TCR'° thymocytes in vivo. Science 250: 1720-1723.

Nagata S and Golstein P (1995) The Fas death factor. Science 267: 1449-1456.

Nemanzee DA and Biirki K (1989) Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes. Nature 337: 562-566.

Rathmell JC, Townsend SE, Xu JC, Flavell RA and Goodnow CC (1996) Expansion or elimination of B cells in vivo: Dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell 87: 319-329.

Russell JH (1995) Activation-induced death of mature T cells in the regulation of immune responses. Current Opinion in Immunology 7: 382-388.

Russell JH, Rush B, Weaver C and Wang R (1993) Mature T cells of autoimmune Ipr/lpr mice have a defect in anti-gen-stimulated suicide. Proceedings of the National Academy of Sciences of the USA 90: 4409^1413.

Singer GG and Abbas AK (1994) The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic micc. Immunity 1: 365-371.

Takashi R, Tanaka M, Brannan CI et al (1994) Generalized lymphoproliferative disease in mice caused by a point mutation in the Fas ligand. Cell 76: 969-976.

van Meerwijk JP, Marguerat S, Lees RK et al (1997) Quantitative impact of thymic clonal deletion on the T cell repertoire. Journal of Experimental Medicine 185: 377-383.

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