Further reading

Carter P and Merchant AM (1997) Engineering antibodies for imaging and therapy. Current Opinion in Biotechnology 8: 449—454. De-Jonge J, Brissinck J, Heirman C et al (1995) Production and characterization of bispecific single-chain antibody fragments. Molecular Immunology 32: 1405-1412. de-Kruif J and Logtenberg T (1996) Leucine zipper dimer-ized bivalent and bispecific scFv antibodies from a semisynthetic antibody phage display library. Journal of Biological Chemistry 271: 7630-7634. Demanet C, Brissinck J, De-Jonge J and Thielemans K (1996) Bispecific antibody-mediated immunotherapy of the BCL1 lymphoma: increased efficacy with multiple injections and CD28-induced costimulation. Blood 87: 4390—4398.

DeSilva BS and Wilson GS (1995) Solid phase synthesis of bifunctional antibodies. Journal of Immunological Methods 188: 9-19. Fanger MW, Segal DM and Romet-Lemonne J-L (1991) Bispecific antibodies and targeted cellular cytotoxicity. Immunology Today 12: 51-54. Ito M and Moran T (1989) Sideways killing mediated by either anti-TCR or anti-T3 antibodies. International Reviews of Immunology 4: 133-145. Jost CR, Titus JA, Kurucz I and Segal DM ( 1996) A single-chain bispecific Fv2 molecule produced in mammalian cells redirects lysis by activated CTL. Molecular Immunology 33: 211-219. Jung G and Müller Eberhard HJ (1988) An in vitro model for tumor immunotherapy with antibody heteroconjugates. Immunology Today 9: 257-260. Renner C and Pfreundschuh M (1995) Tumor therapy by immune recruitment with bispecific antibodies. Immunology Reviews 145: 179-209. Starz UD and Bevan MT (1989) Redirecting the cellular immune response. International Reviews of Immunology 4: 159-175. Tibben JG, Boerman OC, Massuger LF, Schijf CP, Claes-sens RA and Corstens FH (1996) Pharmacokinetics, biodistribution and biological effects of intravenously administered bispecific monoclonal antibody OC/TR F(ab')2 in ovarian carcinoma patients. International Journal of Cancer 66: 477-483.

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