Further reading

Adderson EE, Johnston JM, Shackelford PC and Carroll WM (1992) Development of the human antibody repertoire. Pediatric Research 32: 257-262. Hanson LA, Soderstrom T and Oxelius V-A (cds) (1986) Immunoglobulin subclass deficiencies. Monographs in Allergy 20.

Honjo T and Alt FW (1995) Immunoglobulin Genes, 2nd edn. London: Academic Press. Irigoyen M, Manheimer-Lory A, Gaynor B and Diamond B (1994) Molecular analysis of the human immunoglobulin V\ II gene family. Journal of Clinical Investigation 94: 532-538. Jefferis R (1991) Structure-function relationships in human immunoglobulins. Netherlands Journal of Medicine 39: 188-198. Jefferis R, Pound J and Goodall M (1994) Effector mechanisms activated by human IgG subclass antibodies: clinical and molecular aspects. Annales de Biologic Clinique (Paris) 52: 57-65. Kuijpers TW, Weening RS and Out TA (1992) IgG subclass deficiencies and recurrent pyogenic infections, unresponsiveness against bacterial polysaccharide antigens. Allergologia et Immunopathologica 20: 28-33. Pandey J (1993) Genetics of immunoglobulins. Immunology Series 58: 103-116. Shakib F (ed) (1986) Basic and clinical aspects of IgG sub classes. Monographs in Allergy 19. Tan LK, Shopes RJ, Oi VT and Morrison SL (1990) Influ ence of the hinge region on complement activation, Clq binding, and segmental flexibility in chimeric human immunoglobulins. Proceedings of the National Academy of Sciences of the USA 87: 162-166.

Zeggers BJM, Rijkers GT and Stoop JW ( 1991 ) I lumoral immunodeficiency: from description to the cellular and molecular basis of the defect. Netherlands Journal of Medicine 39: 199-208.

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