Further reading

Abbas AK, Murphy KM and Sher A (1996) Functional diversity of helper T lymphocytes. Nature 383: 787-793.

Alcami A and Smith GL (1995) Cytokine receptors encoded by poxviruses: a lesson in cytokine biology. Immunology Today 16: 474^178. Alms WJ, Atamas SP, Yurovsky VV and White B (1996) Generation of a variant of human interleukin-4 by alternative splicing. Molecular Immunology 33: 361-370.

Arend WP and Dayer J-M (1995) Inhibition of the production and effects of IL-1 and TNI'« in rheumatoid arthritis. Arthritis and Rheumatism 38: 151-160. Bazzoni F and Beutler B (1996) The tumor necrosis factor ligand and receptor families. New England Journal of Medicine 334: 1717-1725. Burger D, Chicheportiche R, Giri J and Dayer JM (1995) The inhibitory activity of human interleukin-l receptor antagonist is enhanced by type II interleukin-l soluble receptor and hindered by type I interleukin-l soluble receptor. Journal of Clinical Investigation 96: 38—41. Chizzolini C, Chicheportiche R, Burger D and Dayer JM (1997) Human TH1 cells preferentially induce interleukin (IL-1) while Tn2 cells induce IL-1 receptor antagonist production upon cell/cell contact with monocytes. European Journal of Immunology 27: 171-177. Dayer J-M and Arend WP (1997) Cytokines and growth factors. In: Kelley WN, Harris ED, Ruddy S and Sledge CB (eds) Textbook of Rheumatology, 5th edn, pp 267-286. Philadelphia: Saunders. Dinarello CA (1996) Biologic basis for interleukin-l in disease. Blood 87: 2095-2147.

Enssle K and Schulz G (1995) Regulation of interleukin-4 activity by soluble interleukin-4 receptors. Journal of Clinical laboratory Analysis 9: 450-455.

Femandez-Botran R, Chilton PM and Ma Y (1996) Soluble cytokine receptors: Their roles in immunoregul-ation, disease, and therapy. Advances in Immunology 63: 269-336.

Gabay C, Gay-Crosier F, Roux-Lombard P et al (1994) Elevated serum levels of interleukin-l receptor antagonist in polymyositis-dermatomyositis: a biological marker of disease activity with a possible role in the lack of acute-phase protein response. Arthritis and Rheumatism 37:1744-1751.

Gabay C, Cakir N, Moral F et al (1997) Circulating levels of tumor necrosis factor soluble receptors in systemic lupus erythematosus are significantly higher than in other rheumatic diseases and correlate with disease activity. Journal of Rheumatology 24: 303-308.

Gillessen S, Carvajal D, Ling P et al (1995) Mouse interleu-kin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist. European Journal of Immunology 25: 200-206.

Hansen MB (1996) Human cytokine autoantibodies. Characteristics, test procedures and possible physiological and clinical significance. APMIS Supplement 59: 1-33.

Heinrich PC, Graeve L, Rose-John S et al (1995) Membrane-bound and soluble interleukin-6 receptor: studies on structure, regulation of expression, and signal transduction. Annals of the New York Academy of Sciences 762: 222-227.

Lennard AC (1995) Interleukin-l receptor antagonist. Critical Reviews in Immunology 15: 77-105.

Mantovani A, Muzio M, Ghezzi P, Colotta F and Introna M (1996) Negative regulators of the interleukin-l system: receptor antagonists and a decoy receptor. International Journal of Clinical Laboratory Research 26: 7-14.

Moreland LW, Baumgartner SW, Schiff MH et al (1497' Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. New England Journal of Medicine .337: 141-197.

Moreland LW, Heck jr LW and Koopman WJ (1997i Biologic agents for treating rheumatoid arthritis. Concepts and progress. Arthritis and Rheumatism 40: 397-409.

Pelletier J-P, Caron JP, Evans C et al (1997) In vivo suppression of early experimental osteoarthritis by interleukin-l receptor antagonist using gene therapy. Arthritis and Rheumatism 40: 1012-1019.

Seckinger P, Isaaz S, Dayer J-M (1988) A human inhibitor of tumor necrosis factor a. Journal of Experimental Medicine 167: 1511-1516.

Seckinger P, Lowenthal JW, Williamson K, Dayer J-M, MacDonald HR (1987) A urine inhibitor of interleukin I activity that blocks ligand binding. Journal of Immunology 139: 1546-1549.

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