Genetics

Familial clustering of sarcoidosis occurs in approximately 5-16% of patients. Within the same family, sibling pairs are most common, followed by mother-daughter pairs and father-son pairs. Monozygotic twins appear more likely to develop sarcoidosis than dizygotic twins, strongly suggesting a genetic component to the disease. The lack of a clear genetic pattern suggests that susceptibility to sarcoidosis is polygenic and associated with environmental factors. Worldwide, HLA studies have shown inconsistent results with associations reported for HLA-DR3 and bilateral hilar adenopathy or erythema nodosum in Swedish patients, B27 and uveitis, B13 and chronic disease, DR5 in Italian patients and DRw52 in Japanese patients.

How To Deal With Rosacea and Eczema

How To Deal With Rosacea and Eczema

Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.

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