Hematopoietic stem cell therapy

After suitable stimulation by cytokines, such as granulocyte colony-stimulating factor (G-CSF), hematopoietic stem cells can be harvested from peripheral blood by cytapheresis in sufficient quantities for stem cell transplantation. This may supplant, in many clinical situations, the collection of stem cells from bone marrow. Applications are autologous stem cell therapy to promote rapid hematopoietic recovery after intensive chemo- and radiotherapy, and allogeneic bone marrow transplantation in hematologic failure and malignancy.

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