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Low-affinity receptor for complexed IgG

Glycosylphosphatidylinositol-anchored form of the CD16 molecule expressed on granulocytes Lactosylceramide (Gal-Glc-Cer type 2 chain) Noncovalently linked to either CD11a, CD11 b or 95

CD11c molecules (a chains) Defect in CD18 results in leukocyte adhesion deficiency (LAD) Part of the B cell antigen receptor complex 95

Phosphoprotein expressed on B cells in three 33, 35, 37 forms (37 and 35 and 33 kDa) as a result of different phosphorylation. This molecule has four membrane-spanning regions Member of the regulator of complement 140

activation (RCA) gene family (see CD35, CD46, CD55). Molecule functions as C3d receptor (CR2) and serves also as receptor for Epstein-Barr virus

Functions as an adhesion molecule with a sialic 135, 140 acid binding capacity for carbohydrates which were found e.g. on CD45RO, CDw75 and CDw76 molecules The extracellular region contains a C-type lectin 45-50

domain (see CD69, CD72, CD94, CD161) Glycophosphoinositol-linked, extremely 42

glycosylated protein. Possible counter-receptor for CD62P

Has low-affinity IL-2 binding capacity. By 60

noncovalently associating with the CDw122 molecule and the CD132 (common to CD124 and CD127) molecule, it forms the high-affinity IL-2 receptor complex Has also collagen binding properties. Associated 110 with adenosine deaminase and CD45 molecules Member of the tumor necrosis factor (TNF)/nerve 55 growth factor (NGF) receptor family (see CD30, CD40, CD95, CD120a, CD120b, CD134, CDw137). Counter-receptor for CD70 Counterreceptor for CD80, CD86 and B7-3 44

molecules

/3 chain of the VLA protein family (CD49 130

molecule family), however, can also associate with other integrin a chains (see CD51) Member of the TNF/NGF receptor family (see 105 CD27, CD40, CD95, CD120a, CD120b, CD134, CDw137). Counter-receptor for CD153

Table 1 Cintinued

Other name (s)

Main reactivity of mAbs

Short characteristic of the CD molecule

Molecular weight reduced (kDa)

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