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Cytoplasm / j

l V\ _ Endssomal

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Figure 1 The overall structural organization of li chain, showing the important functional domains of this type II transmembrane protein.

Figure 1 The overall structural organization of li chain, showing the important functional domains of this type II transmembrane protein.

chains, having its cytoplasmic tail at the N-terminus, followed by the transmembrane domain. The luminal portion of li chain responsible for its assembly into oligomeric complexes is located further towards the C-terminus.

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