Clearly the most impressive medical indication of the acquired immune response is vaccination. The simple and elegant theory of vaccination is that induction of a primary immune response by a nonpathogenic form of an antigen leads to immunity of the infectious form. Common types of vaccines are attenuated pathogen, related noninfectious antigen, and purified proteins from the pathogen. Examples of all of these vaccines have been used to induce a primary immune response that confers acquired immunity.
See also: Affinity maturation; Antigen-presenting cells; Antigens, T dependent and independent; Immune response; Immunoglobulin class switching; Maternal antibodies; Memory, immunological; Vaccines.
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