Bone marrow transplants

HLA typing is essential to bone marrow transplantation. Most of the transplants performed are between HLA-identical siblings, which provides the highest rate of success. One-quarter of the siblings are HLA identical. Transplants are not all successful, in that graft-versus-host reactions often occur even with HLA-identical sibling donor grafts due to incompatibility for minor histocompatibility antigens. Recurrence of leukemia is also often a problem.

In recent years, volunteer bone marrow donor

Table 1 Complete listing of recognized HLA specificities and alleles

HLA HLA alleles specificity

A1 A*0101, 0102

A2 A*0201, 0202, 0204-0209, 0211-0214, 0216-0222

A203 A*0203

A210 A*0210

A3 A*0301, 0302

A9 A*2410

A10 A*2502, A*6603

A11 A*1101-1104

A2403 A*2403

A25(10) A*2501

A26(10) A*2601-2608

A29(19) A*2901 -2903

A30(19) A*3001 -3004

A32(19) *A3201-3202

A34(10) A*3401-3402

A36 A*3601

A43 A*4301

A66(10) A*6601 -6602

A28 A*6803

A68(28) A*68011-68012, *6802

A69(28) A*6901

A19 A*7403

A74(19) A*7401-7402

A80 A*8001

B7 B*0702, *0704-0708

B703 B*0703

B8 B*0801-0804

B13 B*1301-1304

B18 B*1801-1805

B27 B*2701-2704, 8*27052-53, B*2706-7, B*2709-2711

B2708 B*2708

B37 B*3701 -02

B3901 B*39011, *39013

B3902 B*39021 -22

B16 B*3905

B40 BM003-4

B4005 B*4005

B41 BM101-2

B12 BM409-10

B45(12) B*4501

B46 B*4601

B47 BM701-2

B49(21) B*4901

B50(21) B*5001

B5 B*5106

B5102 B*51021-2

B5103 B*5103

Table 1 Continued

HLA HLA alleles specificity

How To Bolster Your Immune System

How To Bolster Your Immune System

All Natural Immune Boosters Proven To Fight Infection, Disease And More. Discover A Natural, Safe Effective Way To Boost Your Immune System Using Ingredients From Your Kitchen Cupboard. The only common sense, no holds barred guide to hit the market today no gimmicks, no pills, just old fashioned common sense remedies to cure colds, influenza, viral infections and more.

Get My Free Audio Book

Post a comment