Treatment and Outcome

Despite the fact that HIV patients are immune suppressed, in various series their outcome whether treated medically or surgically does not seem to differ from non-HIV patients with infective endocarditis. In a retrospective study Mestres et al. [42] described 31 HIV-1-infected patients that underwent cardiac surgery due to infective endocarditis. Hospital mortality was 22.6. Nine patients (37.5%) died between 2 and 171 months (mean 54.5) after surgery. Overall mortality was 50%. In this small European series, cardiac surgery did not blunt CD4 response induced by antiretrovirals. The late causes of death were not AIDS-related events.

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