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accelerate their gain over time. Either of these mechanisms would slow down the encode process of an otherwise normal (maybe cortical) accumulation of pulses generated by a hypothetical internal clock. Dysfunction of the indirect pathway, conceived to normally suppress conflicting memory patterns, would instead release commands (time is up) related to unwanted (not relevant to the context) memories producing the coupling — i.e., migration — effect seen on decoding. In other words, we considered the circuit of the basal ganglia as playing a role in both influencing the encode process via the direct pathway and suppressing potentially conflicting memories via the indirect pathway during retrieval. The results obtained with pallidal DBS failed to confirm this hypothesis.

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