Scientific Background

The term cloning has many meanings. Scientific meanings are reasonably clear, although they have become more complex since technologies for reproducing mammals by cloning from nuclei of somatic cells were demonstrated by Keith H. Campbell and colleagues (1996) and Ian Wilmut and colleagues (1997), the latter resulting in Dolly, the first sheep cloned from an adult somatic cell. Since then, there has been an explosion of research in this area, and the terminology has sometimes been controversial. This entry will cover scientific aspects of both reproductive and therapeutic cloning.

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