Info

What is the race/ ethnicity/country of origin of woman (and partner)?

African-American

Ashkenazi-Jewish

Southeast Asian, Greek Southern Italian European-American

Offered sickle cell carrier testing

Offered Tay-Sachs (and possibly an Ashkenazi-Jewish panel, including, e.g. Canavan disease) carrier testing Standard blood work-up looking for anemia may be used to suggest need for a next step Offered cystic fibrosis carrier testing; some places may make this offer to ALL pregnant women

If both partners are carriers, referral for amniocentesis/CVS If both partners are carriers, referral for amniocentesis/CVS

Offered alpha or beta thalassemia carrier testing If both partners are carriers, referral for amniocentesis/CVS

If both partners are carriers, referral for amniocentesis/ CVS

Are you beginning prenatal care <16 weeks of pregnancy

Yes

Offered multiple marker screening

Suggested one-age screening protocol

If result is positive HIGH, referred for ultrasound If result is positive LOW, referred for amniocentesis

If result is inconclusive, referred for amniocentesis

Are you beginning prenatal care in the first trimester?

Yes

Offered PAPP-A screening, adjusted by maternal age, and ultrasound to assess fetal nuchal translucency

If joint results are positive, referred for amniocentesis

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