Investigational Applications

Research in deep brain stimulation is blurring the disciplinary boundaries between neurology and psychiatry. French investigators have discovered that DBS caused transient acute depression in a patient with Parkinson's disease whose motor function had improved markedly through DBS intervention (Bejjani et al.). Investigators are conducting clinical trials for the use of DBS for severe psychiatric illnesses such as obsessive—compulsive disorder using techniques pioneered in the treatment of movement disorders (Roth et al.; Rapoport and Inoff-Germain). Nicholas D. Schiff and colleagues have proposed the use of DBS for the modulation of consciousness after severe traumatic brain injury (Schiff, Plum, and Rezai).

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