Predictive Genetic Testing

In June 2000 international leaders of the Human Genome Project (HGP) confirmed that the rough draft of the human genome had been completed a year ahead of schedule. In February 2001 special issues of Science and Nature published the working draft sequence and analysis. A complete, high-quality DNA reference sequence was announced in April 2003, two years earlier than the originally projected completion date. Although a major goal of the HGP is to provide tools to treat, cure, and ultimately prevent genetic disease, the immediate outcome has been a surge in the number of genetic tests that can be used to determine an individual's risk for developing an ever-increasing number of genetic diseases.

The ability to provide currently healthy individuals with DNA-based risk assessments for diseases that will manifest in the future, especially in the absence of effective treatment for those diseases, presents challenges for those at risk, health professionals, and society. This entry explores some of those challenges, concentrating on tests that can detect mutations associated with adult-onset disorders.

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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