Automation

Many methods in molecular biology require high-throughput sample processing, and therefore manual extraction of DNA extraction is not possible.[5] Although many commercial DNA extraction methods can be purchased in tube format, these still require a significant amount of hands-on time in order to add reagents, remove reagents, and perform centrifugation or vacuum steps.[4,5] Efficient methods of DNA extraction that produce pure, high-quality DNA are crucial to the success of PCR and sequencing reactions and the subsequent treatment of disease.[8,9] Current manual methods of DNA extraction are simple and reliable, and are suitable for extraction of low numbers of samples.[10] As the demand for molecular tests increases, new automated methods of DNA extraction will have to be developed to handle larger numbers of clinical samples.[11] There are a number of DNA extraction kits available, based on a 96-well plate format, which allow integration into the workstation of a robotic liquid handler. This allows a much higher throughput of samples, is less work intensive, and produces PCR-ready bacterial DNA.[4,9,11] A number of commercial robotic systems are available for such purposes from companies such as MWG Biotech, Tecan, Qiagen, Beckman, and Roche.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

Get My Free Ebook


Post a comment