Clinical Definition

In 1986, an international group of experts agreed on diagnostic criteria to distinguish classical MFS from many related disorders. These criteria constitute what is currently referred to as the ''Berlin nosology.''[1] Patients are diagnosed based on the involvement of the skeletal system and two other systems with at least one major manifestation (ectopia lentis, aortic dilation/dissection, or dural ectasia). Patients with an affected first-degree relative are required to have involvement of at least two other systems, with one major manifestation preferred but not required. This nosology has been revised in 1996 and referred to as the ''Ghent nosology.''[2] This new formulation requires involvement of three systems with two major diagnostic manifestations. It provides for major skeletal manifestations and considers affected first-degree relatives or molecular data as major diagnostic criteria.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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