Clinical Description Presentation

Patients with VHL are predisposed to develop tumors, predominantly retinal and central nervous system (brain and spinal cord) hemangioblastomas (HABs), clear cell renal cell carcinomas (CCRCCs), pheochromocytoma (PHEO), and, occasionally, extraadrenal paragangliomas (PGLs) (reviewed in Ref. [4]). Clear cell renal cell carcinomas are the major cause of morbidity. In addition, VHL patients may develop endolymphatic sac tumors, pancreatic islet cell tumors, papillary cystade-nomas of the epididymus (males), or, occasionally, broad ligament (females) and visceral cysts of the kidneys and pancreas.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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