Clinical Features

Haas[4] provided the first clinical description of the disease in 1898. The phenotype of RS and its variability have been described by several authors.[5-8] The predominant phenotype includes foveal and peripheral retinoschisis and vitreous veils of partial retinal layers in the vitreous. Fundus examination may show the Mizuo phenomenon, an inner retinal sheen that occurs with the onset of light exposure after a period of dark adaptation.[9] An area of schisis may leave a retinal vessel unsupported in the vitreous cavity, called a ''congenital vascular veil.'' Affected males are identified between 5 and 10 years of age with poor visual acuity, typically 20/60-20/120.[10] A small number of patients present in infancy with bilateral bullous retinal detach-ment.[11] Visual impairment may be stable until age 50-60 when macular atrophy results in further central vision loss.[5,10] Acute sight threatening complications such as retinal detachment and vitreous hemorrhage occur in 10% and 5% of patients, respectively. Variation in disease presentation and disease progression is observed among affected members of the same family. Carrier females remain asymptomatic and generally have no signs of the condition.[10] Rarely, examination of the peripheral retina of a female carrier may show white flecks or areas of schisis.[12] The ERG is not able to detect carriers.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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