Clinical Management

The management of OI focuses on minimizing fractures and maximizing function in all aspects of the child's life. Until recently, the correction of deformities, intramedul-lary rodding of long bones, orthotic support, muscle strengthening, and mobility devices, such a wheelchairs, were the mainstays of treatment.[11] The recombinant human growth hormone has been used to augment growth and bone mass. The greatest potential currently resides in bisphosphonate therapy. Bisphosphonates as potent inhibitors of bone resorption have been shown to be highly effective in improving bone mass in children with severe forms of OI.[12] As a consequence, the fracture rate was reduced significantly and quality of life increased in all patients. However, in long-term therapy, bone turnover is suppressed to levels lower than those in healthy children, and the consequences of chronically low bone turnover in children with OI are unknown.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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