Many difficulties still encountered with C. difficile infections are linked to the availability of rapid and simple diagnostic assays. The prevention of C. difficile infections is much more complex than just restricting the use of some antibiotic molecules. Almost all classes of antibiotics have been implicated in triggering C. difficile diarrhea. Therefore only rational use of all antibiotics for all infections can have optimal impact, and this could only be achieved when clinical microbiology laboratories would have novel molecular diagnostic assays able to provide detection and identification of microbial pathogens within 1 hr from reception of samples.[26,27] Moreover, C. difficile toxin infections emerge due to complex interactions between the complicated ''normal bowel microflora,'' host response and general health status, environmental factors varying from hospital to hospital, and the genetic potential of C. difficile. It is surprising to realize how little we know about the ecology of the different bacterial species living within our own gut. With the aging population in developed countries and the increasing number of immunosuppressed patients, we are likely to face more opportunistic pathogens such as toxigenic C. difficile. Rapid (< 1 hr) DNA-based tests used to detect these pathogens should become a very important tool of prevention because they will guide physicians and infection control nurses to respond in an efficient manner to nosocomial infections. The economic impact of such rapid response should be tremendous.

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Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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