This entry was intended to review the genomics of C. perfringens and the diseases caused by this bacterium, including CPE-mediated diarrhea, histotoxic infections, and enteritis necroticans. Although some molecular techniques exist for toxin typing (multiplex PCR) and for the diagnosis of CPE-mediated disease (duplex PCR), similar methods for diagnosing histotoxic infections and enteritis necroticans are currently lacking. With the pending completion of additional genome sequencing projects, improved molecular techniques, and rapidly advancing proteomic and genomic applications, C. perfringens researchers will soon gain an increased ability to explore pathogenesis from a molecular perspective. This information should lead to new techniques for diagnosing and treating C. perfringens-mediated infections. The authors hope that this brief chapter adequately summarizes the current state of C. perfringens genetics/molecular diagnostics and human pathogenesis and regret the reliance on review citations due to page limitations.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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