Individual variations in responses to anticancer agents can be partly explained by genetic polymorphisms in their metabolizing enzymes. Genotype-phenotype correlations, however, are still poorly understood because epigenetic influences on gene expression make it difficult to estimate the exact effects of genetic conditions on the activities of metabolizing enzymes. To enable customized and individualized cancer chemotherapies in which the most favorable dosage and drug combination are administered, further studies should focus on parameters that are closely correlated with the pharmacokinetics and pharmacody-namics of an agent and on well-designed clinical trials to evaluate their clinical usefulness.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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