Making a definitive diagnosis is a great challenge for health professionals dealing with NCLs. Accomplishment of the entire diagnostic procedure may require months, years, or decades before genetic approaches are applied, whereas enzymatic and molecular tests need only days or weeks. It is recommended that genetic tests be pursued when a patient shows progressive neurological symptoms, on account of not only time concerns, but also economic concerns. However, the molecular tests need to include more loci/mutations or to employ cutting-edge technology, such as microarray-based hybridization or capillary-based electrophoresis, to increase detection sensitivity.
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The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.