Conclusion

In the next 5 years major efforts will be made to lessen the impact of HIV-1 in the developing world. The reduced costs of antiretroviral to these countries should be extended to cut-price viral load assays and sequencing machinery and kits. This would facilitate the monitoring of HIV-1 and HIV-2 infections in the growing number of infected individuals. New antiretrovirals will become available from new classes of drugs such as fusion inhibitors and integrase inhibitors which will increase the complexity of detection of resistant mutants. Improvements in the current viral load assays will allow more uniform detection of all clades of HIV-1. International standards will reduce the discrepancies observed between the current commercial viral load assays. Real-time PCR technology will further reduce the cost of carrying out viral load detection and improve the speed and sensitivity of current detection systems. The goal of molecular tests should be to detect one copy of HIV-1 RNA/mL of plasma to sequence low copies of HIV-1 RNA for residual resistance and for treatment to reduce levels of virus in plasma to absolute zero.

Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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