The identification of the molecular basis of blood group antigens provides an insight into the generation of gene diversity in humans. A molecular understanding of blood groups has enabled the design of simple assays that may be used to facilitate the provision of blood to patients who require antigen-matched red cells, both by phenotyping the patients to determine their requirements and by phenotyping red cell units.

Transfusion-dependent patients have sickle cell disease, thalassemias, and aplastic anemias, and frequently become alloimmunized. Blood group genotyping contributes substantially to the safety of blood transfusion in these recipients. Although it is unlikely that molecular genotyping will replace hemagglutination any time in the near future, together these techniques have substantial value in the resolution of clinical laboratory problems and, consequently, in the quality of patient care.

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Getting Started With Dumbbells

Getting Started With Dumbbells

The use of dumbbells gives you a much more comprehensive strengthening effect because the workout engages your stabilizer muscles, in addition to the muscle you may be pin-pointing. Without all of the belts and artificial stabilizers of a machine, you also engage your core muscles, which are your body's natural stabilizers.

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